Code
import requests
import urllib3
urllib3.disable_warnings()
def fetch_uniprot_data(uniprot_id):
url = f"https://rest.uniprot.org/uniprotkb/{uniprot_id}.json"
response = requests.get(url, verify=False) # Disable SSL verification
response.raise_for_status() # Raise an error for bad status codes
return response.json()
def display_uniprot_data(data):
primary_accession = data.get('primaryAccession', 'N/A')
protein_name = data.get('proteinDescription', {}).get('recommendedName', {}).get('fullName', {}).get('value', 'N/A')
gene_name = data.get('gene', [{'geneName': {'value': 'N/A'}}])[0]['geneName']['value']
organism = data.get('organism', {}).get('scientificName', 'N/A')
function_comment = next((comment for comment in data.get('comments', []) if comment['commentType'] == "FUNCTION"), None)
function = function_comment['texts'][0]['value'] if function_comment else 'N/A'
# Printing the data
print(f"UniProt ID: {primary_accession}")
print(f"Protein Name: {protein_name}")
print(f"Organism: {organism}")
print(f"Function: {function}")
# Replace this with the UniProt ID you want to fetch
uniprot_id = "O95727"
data = fetch_uniprot_data(uniprot_id)
display_uniprot_data(data)UniProt ID: O95727
Protein Name: Cytotoxic and regulatory T-cell molecule
Organism: Homo sapiens
Function: Mediates heterophilic cell-cell adhesion which regulates the activation, differentiation and tissue retention of various T-cell subsets (By similarity). Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and IFNG/interferon-gamma secretion by CD8+ T-cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo (PubMed:15811952). Regulates CD8+ T-cell proliferation in response to T-cell receptor (TCR) activation (By similarity). Appears to be dispensable for CD8+ T-cell-mediated cytotoxicity (By similarity). Interaction with SCRIB promotes the late phase of cellular polarization of a subset of CD4+ T-cells, which in turn regulates TCR-mediated proliferation and IFNG, IL17 and IL22 production (By similarity). By interacting with CADM1 on CD8+ dendritic cells, regulates the retention of activated CD8+ T-cells within the draining lymph node (By similarity). Required for the intestinal retention of intraepithelial CD4+ CD8+ T-cells and, to a lesser extent, intraepithelial and lamina propria CD8+ T-cells and CD4+ T-cells (By similarity). Interaction with CADM1 promotes the adhesion to gut-associated CD103+ dendritic cells, which may facilitate the expression of gut-homing and adhesion molecules on T-cells and the conversion of CD4+ T-cells into CD4+ CD8+ T-cells (By similarity)