Miscellaneous

The Miscellaneous Sub-family includes: StructuralAndAdhesion, Other, Unkown_function, and Ligand.

To have direct access to each entry in Miscellaneous main family, click on its uniprot id on the left bar.

Binding site feature correlation

import pandas as pd
import seaborn as sns
import matplotlib.pyplot as plt
sns.set_theme(style="whitegrid")

df_total_flat = pd.read_csv('../database/df_flattened.csv')

miscellaneous_df1 = df_total_flat.loc[df_total_flat['main_classs'] == "Miscellaneous"]
ax = sns.lmplot(
    data=miscellaneous_df1, x="areass", y="hpss",
    hue="sub_classs", col="sub_classs", height=3, col_wrap=3,
)
ax.set(xlabel ="Area", ylabel = "Hydrophobicity")

Binding site feature distribution

fig, axes = plt.subplots(1, 4, figsize=(9, 5))
sns.violinplot(
    y=miscellaneous_df1['sub_classs'],
    x=miscellaneous_df1['hpss'],
    hue=miscellaneous_df1['sub_classs'],
    ax=axes[0]
)
axes[0].set_xlabel('Hydrophobicity')
axes[0].set_ylabel('Miscellaneous sub-family')

sns.violinplot(
    y=miscellaneous_df1['sub_classs'],
    x=miscellaneous_df1['areass'],
    hue=miscellaneous_df1['sub_classs'],
    ax=axes[1]
)
axes[1].set(yticklabels=[])
axes[1].set_ylabel('')
axes[1].set_xlabel('Area')

sns.violinplot(
    y=miscellaneous_df1['sub_classs'],
    x=miscellaneous_df1['seedss_a'],
    hue=miscellaneous_df1['sub_classs'],
    ax=axes[2]
)
axes[2].set(yticklabels=[])
axes[2].set_ylabel('')
axes[2].set_xlabel('Alpha seeds')

sns.violinplot(
    y=miscellaneous_df1['sub_classs'],
    x=miscellaneous_df1['seedss_b'],
    hue=miscellaneous_df1['sub_classs'],
    ax=axes[3]
)
axes[3].set(yticklabels=[])
axes[3].set_ylabel('')
axes[3].set_xlabel('Beta seeds')

plt.tight_layout()
plt.show()