Code
import requests
import urllib3
urllib3.disable_warnings()
def fetch_uniprot_data(uniprot_id):
= f"https://rest.uniprot.org/uniprotkb/{uniprot_id}.json"
url = requests.get(url, verify=False) # Disable SSL verification
response # Raise an error for bad status codes
response.raise_for_status() return response.json()
def display_uniprot_data(data):
= data.get('primaryAccession', 'N/A')
primary_accession = data.get('proteinDescription', {}).get('recommendedName', {}).get('fullName', {}).get('value', 'N/A')
protein_name = data.get('gene', [{'geneName': {'value': 'N/A'}}])[0]['geneName']['value']
gene_name = data.get('organism', {}).get('scientificName', 'N/A')
organism
= next((comment for comment in data.get('comments', []) if comment['commentType'] == "FUNCTION"), None)
function_comment = function_comment['texts'][0]['value'] if function_comment else 'N/A'
function
# Printing the data
print(f"UniProt ID: {primary_accession}")
print(f"Protein Name: {protein_name}")
print(f"Organism: {organism}")
print(f"Function: {function}")
# Replace this with the UniProt ID you want to fetch
= "Q9NQ11"
uniprot_id = fetch_uniprot_data(uniprot_id)
data display_uniprot_data(data)
UniProt ID: Q9NQ11
Protein Name: Polyamine-transporting ATPase 13A2
Organism: Homo sapiens
Function: ATPase which acts as a lysosomal polyamine exporter with high affinity for spermine (PubMed:31996848). Also stimulates cellular uptake of polyamines and protects against polyamine toxicity (PubMed:31996848). Plays a role in intracellular cation homeostasis and the maintenance of neuronal integrity (PubMed:22186024). Contributes to cellular zinc homeostasis (PubMed:24603074). Confers cellular protection against Mn(2+) and Zn(2+) toxicity and mitochondrial stress (PubMed:26134396). Required for proper lysosomal and mitochondrial maintenance (PubMed:22296644, PubMed:28137957). Regulates the autophagy-lysosome pathway through the control of SYT11 expression at both transcriptional and post-translational levels (PubMed:27278822). Facilitates recruitment of deacetylase HDAC6 to lysosomes to deacetylate CTTN, leading to actin polymerization, promotion of autophagosome-lysosome fusion and completion of autophagy (PubMed:30538141). Promotes secretion of exosomes as well as secretion of SCNA via exosomes (PubMed:24603074, PubMed:25392495). Plays a role in lipid homeostasis (PubMed:31132336)